Fiora Runes explained
There's one set of runes for Fiora on patch
12.10
that is the clear favorite for LoL players and pros alike. The best Fiora Runes on the position 
Top are Precision as the primary path and
Resolve as the secondary path with a pick rate of 56%. Besides runes you should take a look on Fiora Build and if you are interested in pro matches take a look at Fiora Probuilds. If you want to discuss
Fiora then you should visit the champion subreddit.
Primary runes path on Fiora
Precision improves attack and sustained damage on Fiora troughout the match. Most of high elo players – and our LoL pros in the the major regions – have agreed that
Conqueror is the best keystone rune to run on
Fiora. This keystone rune provides additional power in the later stages of a game. As soon as
Conqueror is fully charged, Fiora deals additional damage and gains life steal. Other primary runes on Fiora are
Triumph,
Legend: Alacrity and
Last Stand.
Triumph restores on Fiora a part of missing health and award bonus gold, if a champion is killed.
Legend: Alacrity grants additional attack speed to Fiora. With
Last Stand you deal more damage while you are at low health.
Secondary runes path on Fiora
When it comes to your secondary path, most
Fiora players prefer to go with
Resolve.
Resolve empowers the survivability of Fiora and increases the tankiness. On the
Resolve path, the best runes for Fiora are
Unflinching and
Second Wind.
Unflinching inceases Fiora tenacity based on your missing health.
Second Wind powers up your sustainablity in lane by healing after taking damage from an enemy champion.
FAQ for Fiora Runes
Which is the best keystone rune on Fiora?
The best keystone rune on Fiora is
Conqueror. This Fiora runes setup is then referred as Fiora Conqueror.