Vayne Runes
A
Adc

Vayne Runes

Night Hunter
Tumble
Q
Silver Bolts
W
Condemn
E
Final Hour
R
Marksman
Marksman
7/6
Win/Loss
<1%
Pick Rate
2%
Ban Rate

Precision + Domination as Vayne Runes

1
2
3
Precision
Precision
Press the Attack
100%
Lethal Tempo
0%
Fleet Footwork
0%
Conqueror
0%
Overheal
46%
Triumph
32%
Presence of Mind
22%
Legend: Alacrity
73%
Legend: Tenacity
3%
Legend: Bloodline
24%
Coup de Grace
42%
Cut Down
57%
Last Stand
2%
Domination
Domination
Cheap Shot
0%
Taste of Blood
>99%
Sudden Impact
<1%
Zombie Ward
<1%
Ghost Poro
<1%
Eyeball Collection
0%
Ravenous Hunter
94%
Ingenious Hunter
0%
Relentless Hunter
0%
Ultimate Hunter
5%
Offense
0%
Offense
>99%
Offense
0%
Offense
>99%
Flex
<1%
Flex
0%
Defense
0%
Flex
96%
Flex
5%
79%
75

Vayne Runes explained

There's one set of runes for Vayne on patch

11.8
that is the clear favorite for LoL players and pros alike. The best Vayne Runes on the position Adc Adc are
Precision
Precision as the primary path and
Domination
Domination as the secondary path with a pick rate of 80%. Besides runes you should take a look on Vayne Build and if you are interested in pro matches take a look at Vayne Probuilds. If you want to discuss
Vayne
Vayne then you should visit the champion subreddit.

Primary path on Vayne

Precision
Precision improves attack and sustained damage on Vayne troughout the match. Most of high elo players – and our LoL pros in the the major regions – have agreed that
Press the Attack
Press the Attack is the best keystone rune to run on
Vayne
Vayne. Vayne has a very easy time activating this rune with basic attacks which synergises well with
Press the Attack
Press the Attack’s damage increase once activated. This is usually followed up by taking
Legend: Alacrity
Legend: Alacrity,
Cut Down
Cut Down and
Coup de Grace
Coup de Grace.

Legend: Alacrity
Legend: Alacrity grants additional attack speed to Vayne. If the enemy team consists of multiple tanks, then the rune
Cut Down
Cut Down is the best choice. Vayne deals with
Coup de Grace
Coup de Grace more damage to targets with low health.

Secondary path on Vayne

When it comes to your secondary path, most

Vayne
Vayne players prefer to go with
Domination
Domination.
Domination
Domination improves burst damage and assassination tools on Vayne. On the
Domination
Domination path, the best runes for Vayne are
Taste of Blood
Taste of Blood and
Ravenous Hunter
Ravenous Hunter.

Taste of Blood
Taste of Blood heals Vayne as soon as you damage an opposing champion.
Ravenous Hunter
Ravenous Hunter is the final rune of the
Domination
Domination path. This rune gives some survivability during short fights and damage trades during the laning phase. The additional health is nothing to scoff at and can mean the difference between winning or losing a battle.