Singed Runes explained
There's one set of runes for Singed on patch
11.8
that is the clear favorite for LoL players and pros alike. The best Singed Runes on the position 
Top are Precision as the primary path and
Inspiration as the secondary path with a pick rate of 65%. Besides runes you should take a look on Singed Build and if you are interested in pro matches take a look at Singed Probuilds. If you want to discuss
Singed then you should visit the champion subreddit.
Primary path on Singed
Precision improves attack and sustained damage on Singed troughout the match. Most of high elo players – and our LoL pros in the the major regions – have agreed that
Conqueror is the best keystone rune to run on
Singed. This keystone rune provides additional power in the later stages of a game. As soon as
Conqueror is fully charged, Singed deals additional damage and gains life steal. This is usually followed up by taking
Presence of Mind,
Legend: Tenacity and
Last Stand.
Presence of Mind helps Singed with the mana problems by restoring missing mana, if a champion is killed. Singed gains extra Tenacity with every additional stage of
Legend: Tenacity. With
Last Stand you deal more damage while you are at low health.
Secondary path on Singed
When it comes to your secondary path, most
Singed players prefer to go with
Inspiration.
Inspiration opens creative opportunities on Singed troughout the match. On the
Inspiration path, the best runes for Singed are
Biscuit Delivery and
Approach Velocity.
Biscuit Delivery is a great rune for laning as it gives additional health and mana, which can help in more aggressive lanes. Singed gains bonus movement speed by
Approach Velocity, while moving toward enemy champions that are immobilized or slowed. This rune is perfect to follow up engages by your teammates.