Quinn Runes explained
There's one set of runes for Quinn on patch
12.10
that is the clear favorite for LoL players and pros alike. The best Quinn Runes on the position 
Top are Precision as the primary path and
Resolve as the secondary path with a pick rate of 44%. Besides runes you should take a look on Quinn Build and if you are interested in pro matches take a look at Quinn Probuilds. If you want to discuss
Quinn then you should visit the champion subreddit.
Primary runes path on Quinn
Precision improves attack and sustained damage on Quinn troughout the match. Most of high elo players – and our LoL pros in the the major regions – have agreed that
Press the Attack is the best keystone rune to run on
Quinn. Quinn has a very easy time activating this rune with basic attacks which synergises well with
Press the Attack’s damage increase once activated. Other primary runes on Quinn are
Presence of Mind,
Legend: Bloodline and
Last Stand.
Presence of Mind helps Quinn with the mana problems by restoring missing mana, if a champion is killed.
Legend: Bloodline gives life steal, which aids in winning damage trades and fights in the later stages of the match. With
Last Stand you deal more damage while you are at low health.
Secondary runes path on Quinn
When it comes to your secondary path, most
Quinn players prefer to go with
Resolve.
Resolve empowers the survivability of Quinn and increases the tankiness. On the
Resolve path, the best runes for Quinn are
Overgrowth and
Bone Plating.
Overgrowth increases your maximum amount of health.
Bone Plating make Quinn overall tankier, by decreasing the amount of poke damage in the early game.
FAQ for Quinn Runes
Which is the best keystone rune on Quinn?
The best keystone rune on Quinn is
Press the Attack. This Quinn runes setup is then referred as Quinn Press the Attack.