Mordekaiser Runes explained
There's one set of runes for Mordekaiser on patch 14.10 that is the clear favorite for LoL players and pros alike. The best Mordekaiser rune paths on the position 
Top are 
Precision as the primary path and 
Resolve as the secondary path with a pick rate of 97%. Besides picking runes on Mordekaiser you should learn how to play Mordekaiser and if you are interested in pro matches take a look on how a pro builds Mordekaiser. If you want to discuss 
Mordekaiser then you should visit the champion subreddit.
Mordekaiser runes from primary path
Precision improves attack and sustained damage on Mordekaiser troughout the match. Most of high elo players – and our LoL pros in the the major regions – have agreed that 
Conqueror is the best keystone rune to run on Mordekaiser. This keystone rune provides additional power in the later stages of a game. As soon as Conqueror is fully charged, Mordekaiser deals additional damage and gains life steal. Other primary runes on Mordekaiser are 
Triumph, 
Legend: Alacrity and 
Last Stand.
Triumph restores on Mordekaiser a part of missing health and award bonus gold, if a champion is killed. Legend: Alacrity grants additional attack speed to Mordekaiser. With Last Stand you deal more damage while you are at low health.
Mordekaiser runes from secondary path
When it comes to your secondary path, most Mordekaiser players prefer to go with Resolve. Resolve empowers the survivability of Mordekaiser and increases the tankiness. On the Resolve path, the best runes for Mordekaiser are 
Revitalize and 
Second Wind.
Revitalize inceases heals and shields you distribute or receive. Second Wind powers up your sustainablity in lane by healing after taking damage from an enemy champion.
FAQ for Mordekaiser Runes
Which is the best keystone rune on Mordekaiser?
The best keystone rune on Mordekaiser is Conqueror. This Mordekaiser runes setup is then referred as Mordekaiser Conqueror.
What runes does Mordekaiser use?
Runes from the paths Precision and Resolve are the most used runes on Mordekaiser. For the exact pick rates of Mordekaiser runes used, you have to study the rune distribution presented.