Kayn Runes explained
There's one set of runes for Kayn on patch
12.18
that is the clear favorite for LoL players and pros alike. The best Kayn rune paths on the position 
Jungle are Precision as the primary path and
Inspiration as the secondary path with a pick rate of 38%. Besides picking runes on Kayn you should learn how to play Kayn and if you are interested in pro matches take a look on how a pro builds Kayn. If you want to discuss
Kayn then you should visit the champion subreddit.
Kayn runes from primary path
Precision improves attack and sustained damage on Kayn troughout the match. Most of high elo players – and our LoL pros in the the major regions – have agreed that
Conqueror is the best keystone rune to run on
Kayn. This keystone rune provides additional power in the later stages of a game. As soon as
Conqueror is fully charged, Kayn deals additional damage and gains life steal. Other primary runes on Kayn are
Triumph,
Legend: Tenacity and
Last Stand.
Triumph restores on Kayn a part of missing health and award bonus gold, if a champion is killed. Kayn gains extra Tenacity with every additional stage of
Legend: Tenacity. With
Last Stand you deal more damage while you are at low health.
Kayn runes from secondary path
When it comes to your secondary path, most
Kayn players prefer to go with
Inspiration.
Inspiration opens creative opportunities on Kayn troughout the match. On the
Inspiration path, the best runes for Kayn are
Cosmic Insight and
Magical Footwear.
Cosmic Insight grants summoner spell and item haste.
Magical Footwear allows Kayn to focus on those essential core items without the need to spend the additional 300 gold on boots.
FAQ for Kayn Runes
Which is the best keystone rune on Kayn?
The best keystone rune on Kayn is
Conqueror. This Kayn runes setup is then referred as Kayn Conqueror.
What runes does Kayn use?
Runes from the paths
Precision and
Inspiration are the most used runes on Kayn. For the exact pick rates of Kayn runes used, you have to study the rune distribution presented.