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Kai'Sa Runes
C
Adc

Kai'Sa Runes

Second Skin
Icathian Rain
Q
Void Seeker
W
Supercharge
E
Killer Instinct
R
Marksman
Marksman
30/10
Win/Loss
1%
Pick Rate
<1%
Ban Rate

Domination + Inspiration as Kai'Sa Runes

1
2
3
Domination
Domination
Electrocute
0%
Predator
0%
Dark Harvest
0%
Hail of Blades
100%
Cheap Shot
<1%
Taste of Blood
>99%
Sudden Impact
0%
Zombie Ward
14%
Ghost Poro
<1%
Eyeball Collection
85%
Ravenous Hunter
99%
Ingenious Hunter
0%
Relentless Hunter
0%
Ultimate Hunter
1%
Inspiration
Inspiration
Hextech Flashtraption
0%
Magical Footwear
47%
Perfect Timing
0%
Future's Market
0%
Minion Dematerializer
0%
Biscuit Delivery
>99%
Cosmic Insight
28%
Approach Velocity
0%
Time Warp Tonic
25%
Offense
0%
Offense
98%
Offense
0%
Offense
98%
Flex
0%
Flex
0%
Defense
0%
Flex
86%
Flex
17%
75%
176

Kai'Sa Runes explained

There's one set of runes for Kai'Sa on patch

11.19
that is the clear favorite for LoL players and pros alike. The best Kai'Sa Runes on the position Adc Adc are
Domination
Domination as the primary path and
Inspiration
Inspiration as the secondary path with a pick rate of 75%. Besides runes you should take a look on Kai'Sa Build and if you are interested in pro matches take a look at Kai'Sa Probuilds. If you want to discuss
Kai'Sa
Kai'Sa then you should visit the champion subreddit.

Primary path on Kai'Sa

Domination
Domination improves burst damage and assassination tools on Kai'Sa. Most of high elo players – and our LoL pros in the the major regions – have agreed that
Hail of Blades
Hail of Blades is the best keystone rune to run on
Kai'Sa
Kai'Sa. This keystone rune helps you to win short damage trades in your lane by increasing your attackspeed at the beginning of a fight. This is usually followed up by taking
Taste of Blood
Taste of Blood,
Eyeball Collection
Eyeball Collection and
Ravenous Hunter
Ravenous Hunter.

Taste of Blood
Taste of Blood heals Kai'Sa as soon as you damage an opposing champion.
Eyeball Collection
Eyeball Collection is next up. This grants the user additional damage with every killing they score.
Ravenous Hunter
Ravenous Hunter is the final rune of the
Domination
Domination path. This rune gives some survivability during short fights and damage trades during the laning phase. The additional health is nothing to scoff at and can mean the difference between winning or losing a battle.

Secondary path on Kai'Sa

When it comes to your secondary path, most

Kai'Sa
Kai'Sa players prefer to go with
Inspiration
Inspiration.
Inspiration
Inspiration opens creative opportunities on Kai'Sa troughout the match. On the
Inspiration
Inspiration path, the best runes for Kaisa are
Biscuit Delivery
Biscuit Delivery and
Magical Footwear
Magical Footwear.

Biscuit Delivery
Biscuit Delivery is a great rune for laning as it gives additional health and mana, which can help in more aggressive lanes.
Magical Footwear
Magical Footwear allows players to focus on those essential core items without the need to spend the additional 300 gold on boots.