Irelia Runes explained
There's one set of runes for Irelia on patch 14.22 that is the clear favorite for LoL players and pros alike. The best Irelia rune paths on the position 
Top are 
Precision as the primary path and 
Resolve as the secondary path with a pick rate of 67%. Besides picking runes on Irelia you should learn how to play Irelia and if you are interested in pro matches take a look on how a pro builds Irelia. If you want to discuss 
Irelia then you should visit the champion subreddit.
Irelia runes from primary path
Precision improves attack and sustained damage on Irelia troughout the match. Most of high elo players – and our LoL pros in the the major regions – have agreed that 
Conqueror is the best keystone rune to run on Irelia. This keystone rune provides additional power in the later stages of a game. As soon as Conqueror is fully charged, Irelia deals additional damage and gains life steal. Other primary runes on Irelia are 
Presence of Mind, 
Legend: Alacrity and 
Last Stand.
Presence of Mind helps Irelia with the mana problems by restoring missing mana, if a champion is killed. Legend: Alacrity grants additional attack speed to Irelia. With Last Stand you deal more damage while you are at low health.
Irelia runes from secondary path
When it comes to your secondary path, most Irelia players prefer to go with Resolve. Resolve empowers the survivability of Irelia and increases the tankiness. On the Resolve path, the best runes for Irelia are 
Overgrowth and 
Second Wind.
Overgrowth increases your maximum amount of health. Second Wind powers up your sustainablity in lane by healing after taking damage from an enemy champion.
FAQ for Irelia Runes
Which is the best keystone rune on Irelia?
The best keystone rune on Irelia is Conqueror. This Irelia runes setup is then referred as Irelia Conqueror.
What runes does Irelia use?
Runes from the paths Precision and Resolve are the most used runes on Irelia. For the exact pick rates of Irelia runes used, you have to study the rune distribution presented.