Heimerdinger Runes explained
There's one set of runes for Heimerdinger on patch 14.21 that is the clear favorite for LoL players and pros alike. The best Heimerdinger rune paths on the position 
Top are 
Sorcery as the primary path and 
Inspiration as the secondary path with a pick rate of 33%. Besides picking runes on Heimerdinger you should learn how to play Heimerdinger and if you are interested in pro matches take a look on how a pro builds Heimerdinger. If you want to discuss 
Heimerdinger then you should visit the champion subreddit.
Heimerdinger runes from primary path
Sorcery empoweres abilities of Heimerdinger and increases the available champion resources. Most of high elo players – and our LoL pros in the the major regions – have agreed that 
Conqueror is the best keystone rune to run on Heimerdinger. This keystone rune provides additional power in the later stages of a game. As soon as Conqueror is fully charged, Heimerdinger deals additional damage and gains life steal. Other primary runes on Heimerdinger are 
Manaflow Band, 
Absolute Focus and 
Gathering Storm.
This is usually followed up by taking Manaflow Band for additional mana and mana regenaration. Absolute Focus grants additional damage while Heimerdinger is alomst full health. Gathering Storm increases your late game power.
Heimerdinger runes from secondary path
When it comes to your secondary path, most Heimerdinger players prefer to go with Inspiration. Inspiration opens creative opportunities on Heimerdinger troughout the match. On the Inspiration path, the best runes for Heimerdinger are Cosmic Insight and Biscuit Delivery.
Cosmic Insight grants summoner spell and item haste. Biscuit Delivery is a great rune for laning as it gives additional health and mana, which can help in more aggressive lanes.
FAQ for Heimerdinger Runes
Which is the best keystone rune on Heimerdinger?
The best keystone rune on Heimerdinger is Conqueror. This Heimerdinger runes setup is then referred as Heimerdinger Conqueror.
What runes does Heimerdinger use?
Runes from the paths Sorcery and Inspiration are the most used runes on Heimerdinger. For the exact pick rates of Heimerdinger runes used, you have to study the rune distribution presented.