Fiddlesticks Runes explained
There's one set of runes for Fiddlesticks on patch 14.23 that is the clear favorite for LoL players and pros alike. The best Fiddlesticks rune paths on the position 
Jungle are 
Domination as the primary path and 
Inspiration as the secondary path with a pick rate of 95%. Besides picking runes on Fiddlesticks you should learn how to play Fiddlesticks and if you are interested in pro matches take a look on how a pro builds Fiddlesticks. If you want to discuss 
Fiddlesticks then you should visit the champion subreddit.
Fiddlesticks runes from primary path
Domination improves burst damage and assassination tools on Fiddlesticks. Most of high elo players – and our LoL pros in the the major regions – have agreed that 
Electrocute is the best keystone rune to run on Fiddlesticks. This keystone rune provides burst damage, aiding them in nuking down the enemy carries. Other primary runes on Fiddlesticks are 
Cheap Shot, 
Eyeball Collection and 
Ultimate Hunter.
Cheap Shot makes you deal more damage to enemies with impaired movement, which has great synergy with the setup of Fiddlesticks. Eyeball Collection is next up. This grants the user additional damage with every killing they score. Ultimate Hunter scales up Fiddlesticks ultimate haste on every unique champion takedown.
Fiddlesticks runes from secondary path
When it comes to your secondary path, most Fiddlesticks players prefer to go with Inspiration. Inspiration opens creative opportunities on Fiddlesticks troughout the match. On the Inspiration path, the best runes for Fiddlesticks are 
Cosmic Insight and 
Hextech Flashtraption.
Cosmic Insight grants summoner spell and item haste. Having an extra way to decrease the distance with the Hextech Flashtraption will make an engage much easier to pull off.
FAQ for Fiddlesticks Runes
Which is the best keystone rune on Fiddlesticks?
The best keystone rune on Fiddlesticks is Electrocute. This Fiddlesticks runes setup is then referred as Fiddlesticks Electrocute.
What runes does Fiddlesticks use?
Runes from the paths Domination and Inspiration are the most used runes on Fiddlesticks. For the exact pick rates of Fiddlesticks runes used, you have to study the rune distribution presented.