Cho'Gath Runes explained
There's one set of runes for Cho'Gath on patch
12.15
that is the clear favorite for LoL players and pros alike. The best Cho'Gath rune paths on the position 
Top are Resolve as the primary path and
Inspiration as the secondary path with a pick rate of 50%. Besides picking runes on Cho'Gath you should learn how to play Cho'Gath and if you are interested in pro matches take a look on how a pro builds Cho'Gath. If you want to discuss
Cho'Gath then you should visit the champion subreddit.
Cho'Gath runes from primary path
Resolve empowers the survivability of Cho'Gath and increases the tankiness. Most of high elo players – and our LoL pros in the the major regions – have agreed that
Grasp of the Undying is the best keystone rune to run on
Cho'Gath. This keystone rune gives Cho'Gath alot of sustain and helps to force your opposing champion out of the lane. Other primary runes on Cho'Gath are
Demolish,
Second Wind and
Overgrowth.
Demolish increases your pressure on the enemy turrets. This rune will help you to punish bad roams or backtimings of your lane opponent.
Second Wind powers up your sustainablity in lane by healing after taking damage from an enemy champion.
Overgrowth increases your maximum amount of health.
Cho'Gath runes from secondary path
When it comes to your secondary path, most
Cho'Gath players prefer to go with
Inspiration.
Inspiration opens creative opportunities on Cho'Gath troughout the match. On the
Inspiration path, the best runes for Chogath are
Biscuit Delivery and
Approach Velocity.
Biscuit Delivery is a great rune for laning as it gives additional health and mana, which can help in more aggressive lanes. Cho'Gath gains bonus movement speed by
Approach Velocity, while moving toward enemy champions that are immobilized or slowed. This rune is perfect to follow up engages by your teammates.
FAQ for Cho'Gath Runes
Which is the best keystone rune on Cho'Gath?
The best keystone rune on Cho'Gath is
Grasp of the Undying. This Cho'Gath runes setup is then referred as Cho'Gath Grasp of the Undying.
What runes does Cho'Gath use?
Runes from the paths
Resolve and
Inspiration are the most used runes on Cho'Gath. For the exact pick rates of Cho'Gath runes used, you have to study the rune distribution presented.