Ambessa Runes explained
There's one set of runes for Ambessa on patch 15.14 that is the clear favorite for LoL players and pros alike. The best Ambessa rune paths on the position 
Top are 
Resolve as the primary path and 
Inspiration as the secondary path with a pick rate of 72%. Besides picking runes on Ambessa you should learn how to play Ambessa and if you are interested in pro matches take a look on how a pro builds Ambessa.
Ambessa runes from primary path
Resolve empowers the survivability of Ambessa and increases the tankiness. Most of high elo players – and our LoL pros in the the major regions – have agreed that Grasp of the Undying is the best keystone rune to run on 
Ambessa. This keystone rune gives Ambessa alot of sustain and helps to force your opposing champion out of the lane. Other primary runes on Ambessa are Shield Bash, Second Wind and Overgrowth.
Shield Bash powers up your tankiness and empowers your next basic attack while you have a shield. Second Wind powers up your sustainablity in lane by healing after taking damage from an enemy champion. Overgrowth increases your maximum amount of health.
Ambessa runes from secondary path
When it comes to your secondary path, most Ambessa players prefer to go with Inspiration. Inspiration opens creative opportunities on Ambessa troughout the match. On the Inspiration path, the best runes for Ambessa are 
Biscuit Delivery and 
Magical Footwear.
Biscuit Delivery is a great rune for laning as it gives additional health and mana, which can help in more aggressive lanes. Magical Footwear allows Ambessa to focus on those essential core items without the need to spend the additional 300 gold on boots.
FAQ for Ambessa Runes
Which is the best keystone rune on Ambessa?
The best keystone rune on Ambessa is Grasp of the Undying. This Ambessa runes setup is then referred as Ambessa Grasp of the Undying.
What runes does Ambessa use?
Runes from the paths Resolve and Inspiration are the most used runes on Ambessa. For the exact pick rates of Ambessa runes used, you have to study the rune distribution presented.