Nami Runes explained
There's one set of runes for Nami on patch
12.10
that is the clear favorite for LoL players and pros alike. The best Nami Runes on the position 
Support are Domination as the primary path and
Inspiration as the secondary path with a pick rate of 51%. Besides runes you should take a look on Nami Build and if you are interested in pro matches take a look at Nami Probuilds. If you want to discuss
Nami then you should visit the champion subreddit.
Primary runes path on Nami
Domination improves burst damage and assassination tools on Nami. Most of high elo players – and our LoL pros in the the major regions – have agreed that
Electrocute is the best keystone rune to run on
Nami. This keystone rune provides burst damage, aiding them in nuking down the enemy carries. Other primary runes on Nami are
Cheap Shot,
Zombie Ward and
Treasure Hunter.
Cheap Shot makes you deal more damage to enemies with impaired movement, which has great synergy with the setup of Nami.
Zombie Ward helps you to expand your vision on the map. Vision is very
crucial in LoL and helps you to avoid unnecessary deaths.
Treasure Hunter is the final rune of the
Domination path. This rune gives Nami additional gold for takedowns. The additional gold is nothing to scoff at and can mean the difference between winning or losing a battle. Nami will gain an additional 70 gold for the first takedown. Nami acquires Bounty Hunter Stacks, which Nami may use to get more takedowns. This rune's power will grow tremendously, and Nami will become wealthy like never been before. Each time a fresh stack of Bounty Hunter Stacks is consumed, Nami will get an additional twenty gold.
Secondary runes path on Nami
When it comes to your secondary path, most
Nami players prefer to go with
Inspiration.
Inspiration opens creative opportunities on Nami troughout the match. On the
Inspiration path, the best runes for Nami are
Biscuit Delivery and
Cosmic Insight.
Biscuit Delivery is a great rune for laning as it gives additional health and mana, which can help in more aggressive lanes.
Cosmic Insight grants summoner spell and item haste.
FAQ for Nami Runes
Which is the best keystone rune on Nami?
The best keystone rune on Nami is
Electrocute. This Nami runes setup is then referred as Nami Electrocute.