Tryndamere Runes explained
There's one set of runes for Tryndamere on patch 14.9 that is the clear favorite for LoL players and pros alike. The best Tryndamere rune paths on the position 
Mid are 
Resolve as the primary path and 
Inspiration as the secondary path with a pick rate of 50%. Besides picking runes on Tryndamere you should learn how to play Tryndamere and if you are interested in pro matches take a look on how a pro builds Tryndamere. If you want to discuss 
Tryndamere then you should visit the champion subreddit.
Tryndamere runes from primary path
Resolve empowers the survivability of Tryndamere and increases the tankiness. Most of high elo players – and our LoL pros in the the major regions – have agreed that 
Grasp of the Undying is the best keystone rune to run on Tryndamere. This keystone rune gives Tryndamere alot of sustain and helps to force your opposing champion out of the lane. Other primary runes on Tryndamere are 
Demolish, 
Second Wind and 
Revitalize.
Demolish increases your pressure on the enemy turrets. This rune will help you to punish bad roams or backtimings of your lane opponent. Second Wind powers up your sustainablity in lane by healing after taking damage from an enemy champion. Revitalize inceases heals and shields you distribute or receive.
Tryndamere runes from secondary path
When it comes to your secondary path, most Tryndamere players prefer to go with Inspiration. Inspiration opens creative opportunities on Tryndamere troughout the match. On the Inspiration path, the best runes for Tryndamere are Magical Footwear and Cosmic Insight.
Magical Footwear allows Tryndamere to focus on those essential core items without the need to spend the additional 300 gold on boots. Cosmic Insight grants summoner spell and item haste.
FAQ for Tryndamere Runes
Which is the best keystone rune on Tryndamere?
The best keystone rune on Tryndamere is Grasp of the Undying. This Tryndamere runes setup is then referred as Tryndamere Grasp of the Undying.
What runes does Tryndamere use?
Runes from the paths Resolve and Inspiration are the most used runes on Tryndamere. For the exact pick rates of Tryndamere runes used, you have to study the rune distribution presented.